Antidepressant drugs are believed to effectively treat depression, but other medications have raised concerns for potentially causing the illness.

Here’s are five medications that may trigger depression:

Accutane
Accutane may effectively treat severe acne, but that medication suffered a serious blemish to its reputation when researchers determined it may also cause depression. From 1982 to 2005, 190 reports of suicides by Accutane users were reported, according to Drugwatch.com.

SPECIAL: Feeling Down? Try These Six Super-Foods That Beat the Blues

Accutane was created by Roche Pharmaceuticals and approved for use in 1982 by the Food and Drug Administration. The FDA in 1998 notified physicians that Accutane "may cause depression, psychosis, and rarely, suicidal ideation, suicide attempts and suicide," reported LawyersandSettlements.com. Roche stopped making Accutane in 2009, but generic versions of that drug, known as isotretinoin, remain available.

Statins
Statins, which are most commonly prescribed to lower cholesterol, prevent heart attacks, and stave off damage from coronary artery disease, have been found to sometimes cause depression, according to WebMD. Statins include Lipitor, Zocor, Mevacor, Lescol, and Pravachol.

Contraceptives
Research published in 2010 in the Cochrane Database of Systematic Reviews indicated contraceptives — including those delivered by a vaginal ring or patch — can lead to depression in some people, said Everyday Health.

Benzodiazepines
A group of central nervous system depressants used to relax muscles and treat anxiety and insomnia, benzodiazepines have also been reported to cause depression in some patients, according to WebMD. It said examples of this type of medication include Valium, Xanax, Dalmane, Halcion, Klonopin, Librium, and Ativan.

ALERT: Depression Relief: 4 Supplements Better Than Antidepressants

Opioids
Opioids are prescribed to ease moderate to severe physical pain but have at times been reported to trigger emotional pain and depression in patients, WebMD reported. It indicated opioids, which have a high potential for addiction and abuse, include OxyContin, codeine, morphine, Percodan, and Demerol.

Related Stories:

• 5 Best Foods That Ease Depression and Anxiety
• Antidepressant Drugs: Side Effects and Risks