Though the first fecal microbiota transplants(FMTs) to treat Clostridium difficile were performed on around 1958, the Beatles' 1967 hit "It's Getting Better All the Time" probably wasn’t referring to the treatment's growing effectiveness. But it's true — the success of FMTs is doing just that.
Those of us in the medical community are well aware that FMT has about a 90 percent cure rate for C. difficile bacterial infections. That's big news, because such infections can be lethal, especially if you're elderly or have a compromised immune system.
In 2012, C. difficile sickened 347,000 Americans, and 14,000 died. Despite that, the total number of FMTs performed in the U.S. remains below 500.
But a new follow-up study has shown that when antibiotic treatments fail to help people with recurring C. diff, fecal transplants can prevent it for six months and counting. So, we're wondering, with a 90 percent or better success rate, is it time for FMT to be the first-line treatment for C. diff?
Side effects of FMTs are virtually nonexistent, while antibiotic use contributes to development of antibiotic-resistant bacterial strains, such as MRSA.
True, one woman became obese after receiving a FMT from her daughter (who wasn't overweight at the time, but became so later), but that just means donors should be screened more carefully as we learn more about which gut bacteria influence good health and which contribute to health problems.
Researchers are working on FMT in pill form, and one day FMT may help obese people lose weight.
Posts by Dr. Mehmet Oz, M.D. and Dr. Mike Roizen, M.D.
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