In a study published in the journal Neurology, scientists studied the effects of high- and low-dose vitamin D supplementation in subjects with multiple sclerosis, most of whom had the most severe form — relapsing-remitting MS.
The subjects were randomly given either 10,400 IU or 800 IU of vitamin D3 daily for six months.
Researchers found higher levels of vitamin D3 in the higher-dosed group and no difference in adverse effects.
In the higher-dosed group, there was a reduction in pro-inflammatory molecules that are associated with worsening multiple sclerosis symptoms.
My experience has shown that many multiple sclerosis patients receive a benefit from supplementing with vitamin D3.
About 15 years ago, a patient came to me with multiple sclerosis and very low vitamin D levels.
I supplemented her with 50,000 IU of vitamin D3 per day for two months.
At the end of two months, she no longer needed her wheelchair to get around. To this day, she has still not needed a wheelchair.
Vitamin D supplementation can be toxic. If you are going to use doses higher than 5,000 IU, I suggest working with a knowledgeable practitioner who can monitor your blood chemistry
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