Major business groups say President Barack Obama's health care overhaul is a job killer, and they're launching a multimillion-dollar ad campaign to take that message to voters.

The U.S. Chamber of Commerce, the National Association of Manufacturers, and groups ranging from contractors to retailers said Tuesday the Democratic health care bills would raise their expenses, while failing to control health care costs.

Advertisements will start airing nationwide Wednesday on cable television and shift in a few days to 17 states, targeting moderate and conservative Democrats whose votes are critical to passing the bill in the House. The campaign is estimated to cost between $4 million and $10 million, with the insurance industry paying part of the cost.